Principal Investigator

Omid Farokhzad, M.D.
Associate Professor
Brigham and Women's Hospital
Harvard Medical School
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Our Research

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     Nanotechnology has generated a significant impact in nearly every aspect of science. Our research seeks novel nanomaterials and nanotechnologies in order to develop advanced drug delivery systems with the promise to improve health care. Highly interdisciplinary and translational, our research is focused on multifunctional, nanoparticle-based drug delivery systems. We seek to improve nanoparticle synthesis and formulation and its therapeutic efficacy. Additionally, we develop robust engineering processes to accelerate translation of nanoparticle-based drugs into the drug development pipeline. At the same time, we emphasize a fundamental understanding of the interface between nanomaterials and biological systems, [Read more...]

Group News

Press Release - Targeted Nanoparticle Tested in Patients with Cancer, reports the National Cancer Institute. (04/17/2012) [Read more...]
Welcome Dr. Giuseppe Palmisano to join our team! (04/01/12)
Congratulations to Steffi Sunny for securing a PhD position on the Applied Science and Engineering PhD program at Harvard University! (04/01/12)
Congratulations to Shrey Sindhwani for securing a Physician Scientist Training Program (MD-PhD) position at the University of Toronto! (04/01/12)
Themed nanomedicine review published: "Targeted polymeric therapeutic nanoparticles: design, development and clinical translation". (03/05/2012) Article link
Press Release - Dr Farokhzad is elected to the College of the Fellows of the American Institute of Medical and Biological Engineering. (02/22/2012) [Read more...]
Press Release - Targeted nanoparticles for cancer therapy with internalizing aptamers. (01/03/2012) [Read more...]
Congratulations to Dr. Xiaoyang Xu on the award of his National Cancer Institute funded Ruth L. Kirschstein National Research Service Award Post-doctoral Fellowship! (01/03/2012)
Congratulations to Dr. Jinjun Shi on the award of his National Cancer Institute K99/R00 Career Award! (11/30/2011)
Press Release - Selecta Biosciences initiates Phase 1 clinical study of SEL-068, a first-in-class synthetic nicotine vaccine for smoking cessation and relapse prevention. (11/21/2011) [Read more...]
Congratulations to Dr. Jinjun Shi for his BWH Biomedical Research Institute award! (11/10/2011)
Welcome Dr. Nazila Kamaly to join our team! (01/25/2011)
Press Release - BIND Biosciences initiates Phase 1 clinical study of BIND-014, a first-in-class targeted nanoparticle therapeutic for cancer therapy(01/07/2011) [Read more...]
Welcome Dr. Jun Wu, Dr. Xueqing Zhang and Changwei Ji to join our team! (11/15/2010)
Press Release - New nanoparticles could improve cancer treatment. (10/05/2010) [Read more...]
Press Release - New nanoparticles target cardiovascular disease, article by Juliana Chan et. al. (01/18/2010) [Read more...]
Welcome Dr. Suresh Gadde to join our team! (12/15/2009)
Welcome Dr. Xiaoyang Xu to join our team! (10/19/09)
Welcome Dr. Archana Mukherjee to join our team! (08/19/09)
  [Group News Archive]

Selected Publications

Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile, Hrkach J, Von Hoff D, Ali MM et al, Science Translational Medicine, 4 (2012) 128ra39
Targeted polymeric therapeutic nanoparticles: design, development and clinical translation, N Kamaly, Z Xiao, P Valencia et al., Chem. Soc. Rev, 41 (2012) 2971
Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers, F. Gu, L. Zhang, B. A. Teply, et al., PNAS, 105 (2008) 2586
Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer, V Bagalkot, L Zhang, E Levy-Nissenbaum et al., Nano Lett., 7 (2007) 3065
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo, O. Farokhzad, J. Cheng, B. A. Teply, et al., PNAS, 103 (2006) 6315
  [Browse Publication List...]