Recent Papers in Selected Publications:

Nature Reviews Materials (2020), Oct; 5(11): 847-860.||Science Translational Medicine (2020), July;12(553): eaay1063.||Nature Communications (2020), July;11:3662||Nature Communications (2020), June;11:2778||Science Translational Medicine (2019) Dec;11(523): eaaw1565||Nature Biomedical Engineering (2018) Sep; 2, 850–864||Nature Communications (2017) Oct; 8: 777||Nature Nanotechnology (2017) Sep; 2017, 12, 845–855||Nature Reviews Chemistry (2017) Aug; 2017, 1: 0063||Nature Biomedical Engineering (2017) Feb; 17(1): 0031||Nature Reviews Cancer (2017) Jan; 17(1): 20-37||Nature Reviews Nephrology (2016) Oct; 12(12): 738-753||Science Translational Medicine (2015) Nov; 7(314): 314ra183||Nature Communications (2015) Oct; 6: 8692||Nature (2015) Oct; 526(7571): 47-48||Science (2015) Jun; 348(6241): aaa8205||Science Translational Medicine (2015) Feb; 7(275): 275ra20||Science Translational Medicine (2013) Nov; 5(213): 213ra167||Nature Nanotechnology (2012) Oct; 7(10): 623-629||Science Translational Medicine (2012) Apr; 4(128): 128ra39||Nature Biotechnology (2010) Dec; 28(12): 1267-1270||Nature Nanotechnology (2007) Dec; 2(12): 751-760||etc.


181. Corbo C, Li AA, Poustchi H, Lee GY, Stacks S, Molinaro R, Ma P, Platt T, Behzadi S, Langer R, Farias V, Farokhzad OC. Analysis of the Human Plasma Proteome Using Multi-Nanoparticle Protein Corona for Detection of Alzheimer’s Disease, Adv Healthc Mater (2020), in press. Full Text

180. Liu Y, Wang J, Xiong Q, Hornburg D, Tao W, Farokhzad OC. Nano-Bio Interactions in Cancer: from Therapeutics Delivery to Early Detection, Acc Chem Res (2020), in press. Full Text

179. Islam MA, Rice J, Reesor E, Zope H, Tao W, Lim M, Ding J, Chen Y, Aduluso D, Zetter B, Farokhzad OC, Shi J. Adjuvant-pulsed mRNA vaccine nanoparticle for immunoprophylactic and therapeutic tumor suppression in mice, Biomaterials (2020), in press. Full Text

178. Tang Z, Kong N, Zhang X, Liu Y, Hu P, Mou S, Liljeström P, Shi J, Tan W, Kim JS, Cao Y, Langer R, Leong K, Farokhzad OC, Tao W. A materials science perspective on tackling COVID-19, Nature Reviews Materials (2020), 5(11): 847-860. Full Text

177. Xiao Y, Tang Z, Wang J, Liu C, Kong N, Farokhzad OC, Tao W. Oral insulin delivery platforms: Strategies to address the biological barriers, Angew Chem Int Ed Engl (2020), 59(45): 19787-19795. Full Text

176. Tao W, Yurdagul A, Kong N, Li W, Wang X, Doran A, Feng C, Wang J, Islam MA, Farokhzad OC, Tabas I, Shi J. siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice, Science Translational Medicine (2020), 12(553): eaay1063. Full Text

175. Blume J, Manning W, Troiano G, Hornburg D, Figa M, Hesterberg L, Platt T, Zhao X, Cuaresma R, Everley P, Ko M, Liou H, Mahoney M, Ferdosi S, Elgierari E, Stolarczyk C, Tangeysh B, Xia H, Benz R, Siddiqui A, Carr S, Ma P, Langer R, Farias V, Farokhzad OC. Rapid, Deep and Precise Profiling of the Plasma Proteome with Multi-Nanoparticle Protein Corona, Nature Communications (2020), 11:3662. Full Text

174. Li Y, Ding J, Xu X, Shi R, Saw PE, Wang J, Chung S, Li W, Aljaeid BM, Lee RJ, Tao W, Teng L, Farokhzad OC, Shi J. Dual Hypoxia-Targeting RNAi Nanomedicine for Precision Cancer Therapy, Nano Lett (2020) Jun 1. doi: 10.1021/acs.nanolett.0c00757. Full Text

173. Hu K, Xie L, Zhang Y, Hanyu M, Yang Z, Nagatsu K, Suzuki H, Ouyang J, Ji X, Wei J, Xu H, Farokhzad OC, Liang SH, Wang L, Tao W, Zhang MR. Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy, Nature Communications (2020), 11:2778. Full Text

172. Feng C, Ouyang J, Tang Z, Kong N, Liu Y, Fu L, Ji X, Xie T, Farokhzad OC, Tao W. Germanene-based Theranostic Materials for Surgical Adjuvant Treatment: Inhibiting Tumor Recurrence and Wound Infection, Matter (Cell Press) (2020). doi:10.1016/j.matt.2020.04.022. Full Text

171. Kong N, Ji X, Wang J, Sun X, Chen G, Fan T, Liang W, Zhang H, Xie A, Farokhzad OC, Tao W. ROS-Mediated Selective Killing Effect of Black Phosphorus: Mechanistic Understanding and Its Guidance for Safe Biomedical Applications, Nano Lett. (2020) Apr 15. doi: 10.1021/acs.nanolett.0c01098. Full Text

170. Saw PE, Xu X, Zhang M, Cao S, Farokhzad OC, Wu J. Nanostructure Engineering by Simple Tuning of Lipid Combinations, Angew Chem Int Ed Engl. (2020) Feb 3. doi: 10.1002/anie.201916574. Full Text

169. Son S, Nam J, Zenkov I, Ochyl LJ, Xu Y, Scheetz L, Shi J, Farokhzad OC, Moon JJ. Sugar-Nanocapsules Imprinted with Microbial Molecular Patterns for mRNA Vaccination, Nano Lett. (2020) Feb 10. doi: 10.1021/acs.nanolett.9b03483. Full Text

168. Li S, Saw PE, Lin C, Nie Y, Tao W, Farokhzad OC, Zhang L, Xu X. Redox-responsive polyprodrug nanoparticles for targeted siRNA delivery and synergistic liver cancer therapy, Biomaterials (2020). 234: 119760. Full Text


167. Tang ZM, Kong N, Ouyang J, Feng C, Kim NY, Ji X, Wang C, Farokhzad OC, Zhang H, Tao W. Phosphorus Science-Oriented Designand Synthesis of Multifunctional Nanomaterials for Biomedical Applications, Matter (Cell Press) (2019). doi:10.1016/j.matt.2019.12.007. Full Text

166. Kong N, Tao W, Ling X, Wang J, Xiao Y, Shi S, Ji X, Shajii A, Gan ST, Kim NY, Duda DG, Xie T, Farokhzad OC, Shi J. Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition, Science Translational Medicine (2019) Dec 18;11(523): eaaw1565. Full Text

165. Saw PE, Yao H, Lin C, Tao W, Farokhzad OC, Xu X. Stimuli-Responsive Polymer−Prodrug Hybrid Nanoplatform for Multistage siRNA Delivery and Combination Cancer Therapy, Nano Lett. (2019) Aug 5; DOI: 10.1021/acs.nanolett.9b01660. Full Text

164. Ouyang J, Feng C, Ji X, Li L, Gutti HK, Kim NY, Artzi D, Xie A, Kong N, Liu YN, Tearney GJ, Sui X, Tao W, Farokhzad OC. 2D Monoelemental Germanene Quantum Dots: Synthesis as Robust Photothermal Agents for Photonic Cancer Nanomedicine, Angew Chem Int Ed Engl. (2019) Jul 31; 58, 13405-13410. Full Text

163. Ji X, Kang Y, Ouyang J, Chen Y, Artzi D, Zeng X, Xiao Y, Feng C, Qi B, Kim NY, Saw PE, Kong N, Farokhzad OC, Tao W. Synthesis of Ultrathin Biotite Nanosheets as an Intelligent Theranostic Platform for Combination Cancer Therapy, Adv Sci. (2019) Jul 8; 6 (19), 1901211. Full Text

162. Tao W, Kong N, Ji X, Zhang Y, Sharma A, Ouyang J, Qi B, Wang J, Xie N, Kang C, Zhang H, Farokhzad OC, Kim JS. Emerging two-dimensional monoelemental materials (Xenes) for biomedical applications, Chem Soc Rev. (2019) Apr 26; 48 (11), 2891-2912. Full Text

161. Tao W, Wang J, Parak W, Farokhzad OC, Shi J. Nanobuffering of pH-Responsive Polymers: A Known but Sometimes Overlooked Phenomenon and its Biological Applications, ACS Nano (2019) Apr 10; 13 (5), 4876-4882. Full Text

160. Shi S, Kong N, Feng C, Shajii A, Bejgrowicz C, Tao W, Farokhzad OC. Drug Delivery Strategies for the Treatment of Metabolic Diseases, Adv Healthc Mater. (2019) Feb 11; [Epub ahead of print]. Full Text

159. Ling X, Tu J, Wang J, Shajii A, Kong N, Feng C, Zhang Y, Yu M, Xie T, Bharwani Z, Aljaeid BM, Shi B, Tao W, Farokhzad OC. Glutathione-Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy, ACS Nano (2019) Jan 22; 13 (1), 357-370. Full Text


158. Yu M, Ortega CA, Si K, Molinaro R, Schoen FJ, Leitao R, Xu X, Mahmoudi M, Ahn S, Liu J, Saw PE, Lee IH, Brayner M, Lotfi A, Shi J, Libby P, Jon S, Farokhzad OC. Nanoparticles targeting extra domain B of fibronectin−specific to the atherosclerotic lesion types III, IV, and V−enhance plaque detection and cargo delivery, Theranostics (2018) Nov 15; 8(21): 6008-6024. Full Text

157. Xu X, Wu J, Liu S, Li L, Saw PE, Tao W, Li Y, Krygsman L, Yegnasubramanian S, Marzo AMD, Shi J, Bieberich CJ, Farokhzad OC. Redox-Responsive Nanoparticle-Mediated Systemic RNAi for Effective Cancer Therapy, Small (2018) Sep 17; 14 (41), 1802565. Full Text

156. Islam MA, Xu Y, Tao W, Ubellacker JM, Lim M, Aum D, Lee GY, Zhou K, Zope H, Yu M, Cao W, Oswald JT, Dinarvand M, Mahmoudi M, Langer R, Kantoff PW, Farokhzad OC, Zetter BR, Shi J. Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA, Nature Biomedical Engineering (2018) Sep 17; 2, 850–864. Full Text

155. Tao W, Ji X, Zhu X, Li L, Wang J, Zhang Y, Saw PE, Li W, Kong N, Islam MA, Gan T, Zeng X, Zhang H, Mahmoudi M, Tearney GJ, Farokhzad OC. Two-Dimensional Antimonene-based Photonic Nanomedicine for Cancer Theranostics, Adv Mater (2018) Jul 24; 30 (38), 1802061. Full Text

154. Ling X, Chen X, Riddell IA, Tao W, Wang J, Hollett G, Lippard SJ, Farokhzad OC, Shi J, Wu J. Glutathione-Scavenging Poly(disulfide amide) Nanoparticles for the Effective Delivery of Pt(IV) Prodrugs and Reversal of Cisplatin Resistance, Nano Lett (2018) Jun 19; 18 (7), 4618–4625. Full Text

153. Abadi PPSS, Garbern JC, Behzadi S, Hill MJ, Tresback JS, Heydari T, Ejtehadi MR, Ahmed N, Copley E, Aghaverdi H, Lee RT, Farokhzad OC, Mahmoudi M. Engineering of Mature Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Using Substrates with Multiscale Topography, Adv Funct Mater (2018) Mar 13;28 (19), 1870128. Full Text

152. Behzadi S, Vatan NM, Lema K, Nwaobasi D, Zenkov I, Abadi PPSS, Khan DA, Corbo C, Aghaverdi H, Farokhzad OC, Mahmoudi M. Flat Cell Culturing Surface May Cause Misinterpretation of Cellular Uptake of Nanoparticles, Adv Biosyst (2018) Mar 8; 2, 1800046. Full Text

151. Zheng M, Tao W, Zou Y, Farokhzad OC, Shi B. Nanotechnology-Based Strategies for siRNA Brain Delivery for Disease Therapy, Trends Biotechnol (2018) Feb 5;36(5):562-575. Full Text

150. Zhu X, Ji X, Kong N, Chen Y, Mahmoudi M, Xu X, Ding L, Tao W, Cai T, Li Y, Gan T, Barrett A, Bharwani Z, Chen H, Farokhzad OC. Intracellular Mechanistic Understanding of 2D MoS2 Nanosheets for Anti-Exocytosis Enhanced Synergistic Cancer Therapy, ACS Nano (2018) Feb 6;12 (3), 2922–2938. Full Text


149. Chan WWC, Chhowalla M, Farokhzad OC, Glotzer S, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Kataoka K, Khademhosseini A, Kotov NA, Lee ST, Li Y, Millstone J, Möhwald H, Mulvaney PC, Nel AE, Nordlander PJ, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee ATS, Willson CG, Fernandez LE, Weiss PS. A Big Year Ahead for Nano in 2018, ACS Nano (2017) Dec 26; 11(12):11755-11757. Full Text

148. Bertrand N, Grenier P, Mahmoudi M, Lima EM, Appel EA, Dormont F, Lim JM, Karnik R, Langer R, Farokhzad OC. Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics, Nature Communications (2017) Oct 3; 8:777. Full Text

147. Mahmoudi M, Yu M, Serpooshan V, Wu JC, Langer R, Lee RT, Karp JM, Farokhzad OC. Multiscale technologies for treatment of ischemic cardiomyopathy, Nature Nanotechnology (2017) Sep 6; 2017,12,168–182. Full Text

146. Behzadis S, Luther GA, Harris MB, Farokhzad OC, Mahmoudi M. Nanomedicine for safe healing of bone trauma: Opportunities and challenges, Biomaterials (2017) Sep 4; 2017,146,845–855. Full Text

145. Wang J, Tao W, Chen X, Farokhzad OC, Liu G. Emerging Advances in Nanotheranostics with Intelligent Bioresponsive Systems, Theranostics. (2017) Sep 5; 16(7):3915-3919. Full Text

144. Kakkar A, Traverso G, Farokhzad OC, Weissleder R, Langer R. Evolution of macromolecular complexity in drug delivery systems, Nature Reviews Chemistry (2017) Aug 8; 2017,1:0063. Full Text

143. Yu M, Amengual J, Menon A, Kamaly N, Zhou F, Xu X, Saw PE, Lee SJ, Si K, Ortega CA, Choi WI, Lee IH, Bdour Y, Shi J, Mahmoudi M, Jon S, Fisher EA, Farokhzad OC. Targeted Nanotherapeutics Encapsulating Liver X Receptor Agonist GW3965 Enhance Antiatherogenic Effects without Adverse Effects on Hepatic Lipid Metabolism in Ldlr−/− Mice, Adv Healthc Mater. (2017) Jul 21; [Epub ahead of print]. Full Text

142. Shi B, Zheng M, Tao W, Chung R, Jin D, Ghaffari D, Farokhzad OC. Challenges in DNA Delivery and Recent Advances in Multifunctional Polymeric DNA Delivery System, Biomacromolecules. (2017) Jun 29; [Epub ahead of print]. Full Text

141. Xu X, Saw PE, Tao W, Li Y, Ji X, Bhasin S, Liu Y, Ayyash D, Rasmussen J, Huo M, Shi J, Farokhzad OC. ROS-Responsive Polyprodrug Nanoparticles for Triggered Drug Delivery and Effective Cancer Therapy, Adv Mater. (2017) Jul 6; [Epub ahead of print]. Full Text

140. Tao W, Ji X, Xu X, Ariful IM, Li Z, Chen S, Saw PE, Zhang H, Bharwani Z, Guo Z, Shi J, Farokhzad OC. Antimonene Quantum Dots: Synthesis and Application as Near-Infrared Photothermal Agents for Effective Cancer Therapy, Angew Chem Int Ed Engl. (2017) Jun 22; 56, 11896–11900. Full Text

139. Xu X, Saw PE, Tao W, Li Y, Ji X, Yu M, Mahmoudi M, Rasmussen J, Ayyash D, Zhou Y, Farokhzad OC, Shi J. Tumor Microenvironment-Responsive Multistaged Nanoplatform for Systemic RNAi and Cancer Therapy, Nano Lett. (2017) Jun 21; [Epub ahead of print]. Full Text

138. Behzadi S, Serpooshan V, Tao W, Hamaly M, Alkawareek M, Dreaden E, Brown D, Alkilany A, Farokhzad OC, Mahmoudi M. Cellular Uptake of Nanoparticles: Journey Inside the Cell, Chem Soc Rev. (2017) Jun 6; 46(14):4218-4244. Full Text

137. Zhu X, Tao W, Liu D, Wu J, Guo Z, Ji X, Bharwani Z, Zhao L, Chen X, Zhao X, Farokhazd OC, Shi J. Surface De-PEGylation Controls Nanoparticle-Mediated siRNA Delivery In Vitro and In Vivo, Theranostics. (2017) May 12;7(7):1990-2002. Full Text

136. Saw PE, Yu M, Choi M, Lee E, Jon S, Farokhzad OC. Hyper-cell-permeable micelles as a drug delivery carrier for effective cancer therapy, Biomaterials. (2017) Apr 31;123:118-126. Full Text

135. Xu X, Wu J, Liu Y, Saw PE, Tao W, Yu M, Zope H, Si M, Victorious A, Rasmussen J, Ayyash D, Farokhzad OC, Shi J. Multifunctional Envelope-Type siRNA Delivery Nanoparticle Platform for Prostate Cancer Therapy, ACS Nano. (2017) Mar 28;11(3):2618-2627. Full Text

134. Chopra S, Bertrand N, Lim JM, Wang A, Farokhzad OC, Karnik R. Design of Insulin-Loaded Nanoparticles Enabled by Multistep Control of Nanoprecipitation and Zinc Chelation, ACS Appl Mater Interfaces. (2017) Mar 21;9(13):11440-11450. Full Text

133. Khademhosseini A, Chan WW, Chhowalla M, Glotzer SC, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Kotov NA, Lee ST, Li Y, Möhwald H, Mulvaney PA, Nel AE, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Brinker J, Chen X, Chi L, Crommie M, Dekker C, Farokhzad OC, Gerber C, Ginger DS, Irvine DJ, Kiessling LL, Kostarelos K, Landes C, Lee T, Leggett GJ, Liang XJ, Liz-Marzán L, Millstone J, Odom TW, Ozcan A, Prato M, Rao CN, Sailor MJ, Weiss E, Weiss PS. Nanoscience and Nanotechnology Cross Borders, ACS Nano. (2017) Feb 15;11(2):1123-1126. Full Text

132. Mahmoudi M, Farokhzad OC. Cancer immunotherapy: Wound-bound checkpoint blockade, Nature Biomedical Engineering (2017) Feb 10;17(1):0031. Full Text

131. Shi J, Kantoff PW, Wooster R, Farokhzad OC. Cancer nanomedicine: progress, challenges and opportunities, Nature Reviews Cancer (2017) Jan;17(1):20-37. Full Text


130. Corbo C, Molinaro R, Tabatabaei M, Farokhzad OC, Mahmoudi M. Personalized protein corona on nanoparticles and its clinical implications, Biomater Sci. (2016) Dec 17;3(5):378-387. Full Text

129. Q&A: Omid Farokhzad on Nanomedicine in Cancer, Cancer Discov. (2016) Nov 4;6(12):1300. Full Text

128. Kamaly N, He JC, Ausiello DA, Farokhzad OC. Nanomedicines for renal disease: current status and future applications, Nature Reviews Nephrology (2016) Oct 31;12(12):738-753. Full Text

127. Mahmoudi M, Bertrand N, Zope H, Farokhzad OC. Emerging understanding of the protein corona at the nano-bio interfaces, Nano Today. (2016) Nov 11;11(6):817-832. Full Text

126. Saw PE, Park J, Jon S, Farokhzad OC. A drug-delivery strategy for overcoming drug resistance in breast cancer through targeting of oncofetal fibronectin, Nanomedicine. (2016) Oct 19;13(2):713-722. Full Text

125. Caracciolo G, Farokhzad OC, Mahmoudi M. Biological Identity of Nanoparticles In Vivo: Clinical Implications of the Protein Corona, Trends Biotechnol. (2016) Sep 20;35(3):257-264. Full Text

124. Cisterna B, Kamaly N, Choi W, Tavakkoli A, Farokhzad OC, Vilos C. Targeted nanoparticles for colorectal cancer, Nanomedicine (Lond). (2016) Sep;11(18):2443-56. Full Text

123. Liu Y, Gunda V, Zhu X, Xu X, Wu J, Askhatova D, Farokhzad OC, Parangi S, Shi J. Theranostic near-infrared fluorescent nanoplatform for imaging and systemic siRNA delivery to metastatic anaplastic thyroid cancer, Proc Natl Acad Sci U S A. (2016) Jul 12;113(28):7750-5. Full Text

122.  Xue Y, Xu X, Zhang XQ, Farokhzad OC, Langer R. Preventing diet-induced obesity in mice by adipose tissue transformation and angiogenesis using targeted nanoparticles. Proc Natl Acad Sci U S A. (2016) May 2;17;113(20):5552-7. Full Text

121.  Xu X, Wu J, Liu Y, Yu M, Zhao L, Zhu X, Bhasin S, Li Q, Ha E, Shi J, Farokhzad OC. Ultra-pH-Responsive and Tumor-Penetrating Nanoplatform for Targeted siRNA Delivery with Robust Anti-Cancer Efficacy. Angew Chem Int Ed Engl. (2016) May 3;[Epub ahead of print]. Full Text

120.  Kamaly N, Fredman G, Fojas JJ, Subramanian M, Choi WI, Zepeda K, Vilos C, Yu M, Gadde S, Wu J, Milton J, Carvalho Leitao R, Rosa Fernandes L, Hasan M, Gao H, Nguyen V, Harris J, Tabas I, Farokhzad OC. Targeted Interleukin-10 Nanotherapeutics Developed with a Microfluidic Chip Enhance Resolution of Inflammation in Advanced Atherosclerosis. ACS Nano. (2016 ) Apr 28. Full Text


119.  Chung BL, Toth MJ, Kamaly N, Sei YJ, Becraft J, Mulder WJ, Fayad ZA, Farokhzad OC, Kim Y, Langer R. Nanomedicines for Endothelial Disorders. Nano Today (2015) Dec 1; 10(6):759-776. Full Text

118.  Kamaly N, Yameen B, Wu J, Farokhzad OC. Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release, Chem Rev. (2016) Feb 8;[Epub ahead of print]. Full Text

117.  Zhu X, Wu J, Shan W, Tao W, Zhao L, Lim JM, D’Ortenzio M, Karnik R, Huang Y, Shi J, Farokhzad OC. Polymeric Nanoparticles Amenable to Simultaneous Installation of Exterior Targeting and Interior Therapeutic Proteins, Angew Chem Int Ed Engl. (2016) Feb 5;[Epub ahead of print]. Full Text

116.  Miller MA, Gadde S, Pfirschke C, Engblom C, Sprachman MM, Kohler RH, Yang KS, Laughney AM, Wojtkiewicz G, Kamaly N, Bhonagiri S, Pittet MJ, Farokhzad OC, Weissleder R. Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle, Science Translational Medicine (2015) Nov 18;7(314):314ra183. Full Text

115.  Miller MA, Zheng YR, Gadde S, Pfirschke C, Zope H, Engblom C, Kohler RH, Iwamoto Y, Yang KS, Askevold B, Kolishetti N, Pittet M, Lippard SJ, Farokhzad OC, Weissleder R., Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug, Nature Communications (2015) Oct 27;6:8692. Full Text

114.  Yu M, Wu J, Shi J, Farokhzad OC., Nanotechnology for protein delivery: Overview and perspectives, J Control Release (2015) Oct 13; S0168-3659(15)30180-2. Full Text

113.  Farokhzad OC., Nanotechnology: Platelet mimicry, Nature (2015) Oct 1;526(7571):47-8. Full Text

112.  Yameen B, Vilos C, Choi WI, Whyte A, Huang J, Pollit L, Farokhzad OC., Drug Delivery Nanocarriers from a Fully Degradable PEG-Conjugated Polyester with a Reduction-Responsive Backbone, Chemistry (2015) Aug 3;21(32):11325-9. Full Text

111.  Wu J, Zhao L, Xu X, Bertrand N, Choi WI, Yameen B, Shi J, Shah V, Mulvale M, MacLean JL, Farokhzad OC., Hydrophobic Cysteine Poly(disulfide)-based Redox-Hypersensitive Nanoparticle Platform for Cancer Theranostics, Angew Chem Int Ed Engl. (2015) Aug 3;54(32):9218-23. Full Text

110.  Stary G, Olive A, Radovic-Moreno AF, Gondek D, Alvarez D, Basto PA, Perro M, Vrbanac VD, Tager AM, Shi J, Yethon JA, Farokhzad OC, Langer R, Starnbach MN, von Andrian UH., A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells, Science. (2015) Jun 19;348(6241):aaa8205. Full Text

109.   Zhu X, Xu Y, Solis LM, Tao W, Wang L, Behrens C, Xu X, Zhao L, Liu D, Wu J, Zhang N, Wistuba II, Farokhzad OC, Zetter BR, Shi J., Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment, Proc Natl Acad Sci U S A. (2015) Jun 23;112(25):7779-84. Full Text

108.   Saw PE, Park J, Lee E, Ahn S, Lee J, Kim H, Kim J, Choi M, Farokhzad OC, Jon S., Effect of PEG pairing on the efficiency of cancer-targeting liposomes, Theranostics. 5(2015) 746-54. Full Text

107.   Pridgen EM, Alexis F, Farokhzad OC., Polymeric nanoparticle drug delivery technologies for oral delivery applications, Expert Opin Drug Deliv. (2015) Sep;12(9):1459-73. Full Text

106.  Gabrielle Fredman, Nazila Kamaly, Stefano Spolitu, Jaclyn Milton, Devram Ghorpade, Raymond Chiasson, George Kuriakose, Mauro Perretti, Omid Farokzhad and Ira Tabas, Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice. Science Translational Medicine 7(2015) 275ra20. Full Text

105.  Leoni G, Neumann PA, Kamaly N, Quiros M, Nishio H, Jones HR, Sumagin R, Hilgarth RS, Alam A, Fredman G, Argyris I, Rijcken E, Kusters D, Reutelingsperger C, Perretti M, Parkos CA, Farokhzad OC, Neish AS, Nusrat A. Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair. J Clin Invest, (2015) Mar 2;125(3):1215-27. Full Text

104.  Maldonado RA, LaMothe RA, Ferrari JD, Zhang A, Rossi RJ, Kolte PN, Griset AP, O’Neil C, Altreuter DH, Browning E, Johnston L, Farokhzad OC, Langer R, Scott DW, von Andrian UH, Kishimoto TK. Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance. Proc Natl Acad Sci U S A, (2015) Jan 13;112(2):E156-65. Full Text

103.  Choi WI, Kamaly N, Riol-Blanco L, Lee IH, Wu J, Swami A, Vilos C, Yameen B, Yu M, Shi J, Tabas I, von Andrian UH, Jon S, Farokhzad OC. A Solvent-Free Thermosponge Nanoparticle Platform for Efficient Delivery of Labile Proteins. Nano Lett, 14(2014):6449-55. Full Text

102. Zhang XQ, Even-Or O, Xu X, van Rosmalen M, Lim L, Gadde S, Farokhzad OC, Fisher EA. Nanoparticles Containing a Liver X Receptor Agonist Inhibit Inflammation and Atherosclerosis. Adv Healthc Mater, (2015) Jan 28;4(2):228-36. Full Text


101. Wu J, Kamaly N, Shi J, Zhao L, Xiao Z, Hollett G, John R, Ray S, Xu X, Zhang X, Kantoff PW, Farokhzad OC. Development of Multinuclear Polymeric Nanoparticles as Robust Protein Nanocarriers. Angew Chem Int Ed Engl, 53(2014) 8975-9. Full Text

100.  Yameen B, Choi WI, Vilos C, Swami A, Shi J, Farokhzad OC. Insight into nanoparticle cellular uptake and intracellular targeting. J Control Release, 190(2014) 485-99. Full Text

99.  Swami A, Reagan MR, Basto P, Mishima Y, Kamaly N, Glavey S, Zhang S, Moschetta M, Seevaratnam D, Zhang Y, Liu J, Memarzadeh M, Wu J, Manier S, Shi J, Bertrand N, Lu ZN, Nagano K, Baron R, Sacco A, Roccaro AM, Farokhzad OC, Ghobrial IM. Engineered nanomedicine for myeloma and bone microenvironment targeting. Proc Natl Acad Sci U S A, 111(2014) 10287-92. Full Text

98.  Pridgen EM, Alexis F, Farokhzad OC. Polymeric Nanoparticle Technologies for Oral Drug Delivery. Clin Gastroenterol Hepatol, 12(2014) 1605-10. Full Text

97.  Lim JM, Swami A, Gilson LM, Chopra S, Choi S, Wu J, Langer R, Karnik R, Farokhzad OC. Ultra-High Throughput Synthesis of Nanoparticles with Homogeneous Size Distribution Using a Coaxial Turbulent Jet Mixer. ACS Nano, 8(2014) 6056-65. Full Text

96.  Gadde S, Even-Or O, Kamaly N, Hasija A, Gagnon PG, Adusumilli KH, Erakovic A, Pal AK, Zhang XQ, Kolishetti N, Shi J, Fisher EA, Farokhzad OC. Development of Therapeutic Polymeric Nanoparticles for the Resolution of Inflammation. Adv Healthc Mater, 3(2014) 1448-56. Full Text

95.  Shi J, Xu Y, Xu X, Zhu X, Pridgen E, Wu J, Votruba AR, Archana S, Zetter BR, Farokhzad OC. Hybrid lipid-polymer nanoparticles for sustained siRNA delivery and gene silencing. Nanomedicine, 10(2014) 897-900. Full Text

94.  Ilyinskii PO, Roy CJ, O’Neil CP, Browning EA, Pittet LA, Altreuter DH, Alexis F, Tonti E, Shi J, Basto PA, Iannacone M, Radovic-Moreno AF, Langer RS, Farokhzad OC, von Andrian UH, Johnston LP, Kishimoto TK. Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release. Vaccine, 32(2014) 2882-95. Full Text

93.  Gendelman HE, Balogh LP, Bawa R, Bradbury M, Chang EH, Chiu W, Farokhzad O, Foldvari M, Lanza G, Wang K. Fourth annual conference of the american society for nanomedicine. J Neuroimmune Pharmacol, 1(2014) 1-38. Full Text

92.  Wang AZ, Farokhzad OC. Current progress of aptamer-based molecular imaging. Proc Natl Acad Sci U S A, 55(2014) 353-6. Full Text

91.  Kim Y, Lobatto ME, Kawahara T, Lee Chung B, Mieszawska AJ, Sanchez-Gaytan BL, Fay F, Senders ML, Calcagno C, Becraft J, Tun Saung M, Gordon RE, Stroes ES, Ma M, Farokhzad OC, Fayad ZA, Mulder WJ, Langer R. Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis. Proc Natl Acad Sci U S A, 111(2014) 1078-83. Full Text


90.  Pridgen EM, Alexis F, Kuo TT, Levy-Nissenbaum E, Karnik R, Blumberg RS, Langer R, Farokhzad OC. Transepithelial transport of fc-targeted nanoparticles by the neonatal fc receptor for oral delivery. Science Translational Medicine 5(2013) 213ra167. Full Text

89.  Bertrand N, Wu J, Xu X, Kamaly N, Farokhzad OC. Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology. Adv Drug Deliv Rev, 66C(2013) 2-25. Full Text

88.  Valencia PM, Pridgen EM, Rhee M, Langer R, Farokhzad OC, Karnik R. Microfluidic Platform for Combinatorial Synthesis and Optimization of Targeted Nanoparticles for Cancer Therapy. ACS Nano, 7(2013) 10671-80. Full Text

87.  Xu X, Xie K, Zhang XQ, Pridgen EM, Park GY, Cui DS, Shi J, Wu J, Kantoff PW, Lippard SJ, Langer R, Walker GC, Farokhzad OC. Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug. Proc Natl Acad Sci USA, 110(2013) 18638. Full Text

86.  Kim Y, Fay F, Cormode DP, Sanchez-Gaytan BL, Tang J, Hennessy EJ, Ma M, Moore K, Farokhzad OC, Fisher EA, Mulder WJ, Langer R, Fayad ZA. Single step reconstitution of multifunctional high-density lipoprotein-derived nanomaterials using microfluidics. ACS Nano, 7(2013) 9975. Full Text

85.  Lim JM, Bertrand N, Valencia PM, Rhee M, Langer R, Jon S, Farokhzad OC, Karnik R. Parallel microfluidic synthesis of size-tunable polymeric nanoparticles using 3D flow focusing towards in vivo study. Nanomedicine, 10(2014) 401-9. Full Text

84.  Mieszawska AJ, Kim Y, Gianella A, van Rooy I, Priem B, Labarre MP, Ozcan C, Cormode DP, Petrov A, Langer R, Farokhzad OC, Fayad ZA, Mulder WJ. Synthesis of Polymer-Lipid Nanoparticles for Image-Guided Delivery of Dual Modality Therapy. Bioconjug Chem, 24(2013) 1429. Full Text

83.  Gianella A, Mieszawska AJ, Hoeben FJ, Janssen HM, Jarzyna PA, Cormode DP, Costa KD, Rao S, Farokhzad OC, Langer R, Fayad ZA, Mulder WJ. Synthesis and in vitro evaluation of a multifunctional and surface-switchable nanoemulsion platform. Chem Commun, 49(2013) 9392. Full Text

82.  Johnstone TC, Kulak N, Pridgen EM, Farokhzad OC, Langer R, Lippard SJ. Nanoparticle encapsulation of mitaplatin and the effect thereof on in vivo properties. ACS Nano, 7(2013) 5675. Full Text

81.  Kamaly N, Fredman G, Subramanian M, Gadde S, Pesic A, Fayad ZA, Langer R, Tabas I, Farokhzad OC. Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles. Proc Natl Acad Sci U S A, 10(2013) 6506. Full Text

80.  Prabhakar U, Blakey DC, Maeda H, Jain RK, Sevick-Muraca EM, Zamboni W, Farokhzad OC, Barry ST, Gabizon A, Grodzinski P. Challenges and key considerations of the enhanced permeability and retention effect (EPR) for nanomedicine drug delivery in oncology. Cancer Res, 73(2013) 2412. Full Text

79.  Zhao W, Cui CH, Bose S, Guo D, Shen C, Wong WP, Halvorsen K, Farokhzad OC, Teo GS, Phillips JA, Dorfman DM, Karnik R, Karp JM. Bioinspired multivalent DNA network for capture and release of cells. Proc Natl Acad Sci U S A, 109(2012) 19626. Full Text

78.  Salvador-Morales C, Valencia PM, Gao W, Karnik R, Farokhzad OC. Spontaneous Formation of Heterogeneous Patches on Polymer-Lipid Core-Shell Particle Surfaces during Self-Assembly. Small, 9(2013) 511. Full Text

77.  Xiao Z, Ji C, Shi J, Pridgen EM, Frieder J, Wu J, Farokhzad OC. DNA Self-Assembly of Targeted Near-Infrared-Responsive Gold Nanoparticles for Cancer Thermo-Chemotherapy. Angew Chem Int Ed Engl, 51(2012) 11853. Full Text

76.  Valencia PM, Pridgen EM, Perea B, Gadde S, Sweeney C, Kantoff PW, Bander NH, Lippard SJ, Langer R, Karnik R, Farokhzad OC. Synergistic cytotoxicity of irinotecan and cisplatin in dual-drug targeted polymeric nanoparticles. Nanomedicine (Lond), 5(2013) 687. Full Text


75.  Farokhzad OC. Using ligands to target cancer cells. Clin Adv Hematol Oncol, 8(2012) 543. Full Text

74.  Valencia PM, Farokhzad OC, Karnik R, Langer R. Microfluidic technologies for accelerating the clinical translation of nanoparticles. Nature Nanotechnology 7(2012) 623. Full Text

73.  Zhang XQ, Xu X, Bertrand N, Pridgen E, Swami A, Farokhzad OC. “Interactions of nanomaterials and biological systems: Implications to personalized nanomedicine”. Adv Drug Deliv Rev, 64(2012) 1363. Full Text

72.  Kim Y, Chung BL, Ma M, Mulder WJ, Fayad ZA, Farokhzad OC, Langer R. “Mass Production and Size Control of Lipid-Polymer Hybrid Nanoparticles through Controlled Microvortices”. Nano Lett, 12(2012) 3587. Full Text

71.  Graf N, Bielenberg DR, Kolishetti N, Muus C, Banyard J, Farokhzad OC, Lippard SJ. “a(V)ß(3) Integrin-Targeted PLGA-PEG Nanoparticles for Enhanced Anti-tumor Efficacy of a Pt(IV) Prodrug”. ACS Nano, 6(2012) 4530. Full Text

70.  Xiao Z, Farokhzad OC. “Aptamer-functionalized nanoparticles for medical applications: challenges and opportunities”. ACS Nano, 6(2012) 3670. Full Text

69.  Mieszawska AJ, Gianella A, Cormode DP, Zhao Y, Meijerink A, Langer R, Farokhzad OC, Fayad ZA, Mulder WJ. . “Engineering of lipid-coated PLGA nanoparticles with a tunable payload of diagnostically active nanocrystals for medical imaging”. Chem Commun, 48(2012) 5835. Full Text

68.  Hrkach J, Von Hoff D, Ali MM, Andrianova E, Auer J, Campbell T, De Witt D, Figa M, Figueiredo M, Horhota A, Low S, McDonnell K, Peeke E, Retnarajan B, Sabnis A, Schnipper E, Song JJ, Song YH, Summa J, Tompsett D, Troiano G, Van Geen Hoven T, Wright J, Lorusso P, Kantoff PW, Bander NH, Sweeney C, Farokhzad OC, Langer R, Zale S. “Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile”. Science Translational Medicine 4(2012) 128ra39. Full Text

67.  Radovic-Moreno AF, Lu TK, Puscasu VA, Yoon CJ, Langer R, Farokhzad OC. “Surface Charge-Switching Polymeric Nanoparticles for Bacterial Cell Wall-Targeted Delivery of Antibiotics”. ACS Nano, 6(2012) 4279. Full Text

66.  Kamaly N, Xiao Z, Valencia PM, Radovic-Moreno AF and Farokhzad OC. “Targeted polymeric therapeutic nanoparticles: design, development and clinical translation”. Chem Soc Rev, 41 (2012) 2971. Full Text

65.  Xiao Z, Levy-Nissenbaum E, Alexis F, Lupták A, Teply BA, Chan JM, Shi J, Digga E, Cheng J, Langer R and Farokhzad OC. “Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection”. ACS Nano, 6 (2012) 696. Full Text

64.  Chan JM, Rhee JW, Drum CL, Bronson RT, Golomb G, Langer R and Farokhzad OC. “In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid-polymeric nanoparticles”. Proc Natl Acad Sci U S A, 108 (2012) 19347. Full Text

63.  Wang AZ, Langer R and Farokhzad OC. “Nanoparticle delivery of cancer drugs”. Annu Rev Med, 63 (2012) 185. Full Text


62.  Shi J, Xiao Z, Kamaly N and Farokhzad OC. “Self-assembled targeted nanoparticles: evolution of technologies and bench to bedside translation”. Acc Chem Res, 44 (2011) 1123. Full Text

61.  Valencia PM, Hanewich-Hollatz MH, Gao W, Karim F, Langer R, Karnik R and Farokhzad OC. “Effects of ligands with different water solubilities on self-assembly and properties of targeted nanoparticles”. Biomaterials, 32 (2011) 6226. Full Text

60. Rhee M, Valencia PM, Rodriguez MI, Langer R, Farokhzad OC and Karnik R. “Synthesis of Size-Tunable Polymeric Nanoparticles Enabled by 3D Hydrodynamic Flow Focusing in Single-Layer Microchannels”. Adv Mater, (2011) H79. Full Text

59. Timko BP, Whitehead K, Gao W, Kohane DS, Farokhzad OC, Anderson D, and Langer R. “Advances in Drug Delivery”. Annu Rev Mater Res, 41 (2011) 1. Full Text

58.  Shi JJ, Xiao ZY, Votruba AR, Vilos C and Farokhzad OC. “Differentially Charged Hollow Core/Shell Lipid-Polymer-Lipid Hybrid Nanoparticles for Small Interfering RNA Delivery”. Angew Chem Int Ed Engl, 50 (2011) 7027. Full Text

57.  Gao W and Farokhzad OC. “Self-Propelled Microrockets to Capture and Isolate Circulating Tumor Cells (Perspective) “. Angew Chem Int Ed Engl, 50 (2011) 7220. Full Text

56.  Dhar S, Kolishetti N, Lippard SJ and Farokhzad OC “Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo”. Proc Natl Acad Sci U S A, 108 (2011) 1850. Full Text


55.  Burgess P, Hutt PB, Farokhzad OC, Langer R and Minick S, Zale S. “On firm ground: IP protection of therapeutic nanoparticles”. Nature Biotechnology 28 (2010) 1267. Full Text

54.  Kolishetti N, Dhar S, Valencia PM, Lin LQ, Karnik R, Lippard SJ, Langer R and Farokhzad OC. “Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy”. Proc Natl Acad Sci U S A, 107 (2010) 17939. Full Text

53.  Shi JJ, Votruba AR, Farokhzad OC and Langer R. “Nanotechnology in drug delivery and tissue engineering: From discovery to applications”. Nano Lett, 10 (2010) 3223. Full Text

52.  Gao W, Langer R, and Farokhzad OC. “Poly(ethylene glycol) with observable shedding”. Angew Chem Int Ed Engl, 45 (2010) 6567. Full Text

51.  Wang AZ, Yuet K, Zhang LF, Gu FX, Huynh-Le M, Radovic-Moreno AF, Kantoff PW, Bander NH, Langer R and Farokhzad OC. “ChemoRad nanopartides: a novel multifunctional nanoparticle platform for targeted delivery of concurrent chemoradiation”. Nanomedicine, 5 (2010) 361. Full Text

50.  Valencia PM, Basto PA, Zhang LF, Rhee M , Langer R, Farokhzad OC and Karnik R. “Single-step assembly of homogenous lipid -polymeric and lipid – quantum dot nanoparticles enabled by microfluidic rapid mixing”. ACS Nano, 3 (2010) 1671. Full Text

49.  Mamo T, Moseman EA, Kolishetti N, Morales CS, Shi J, Kuritzkes DR, Langer R, von Andrian U and Farokhzad OC. “Emerging nanotechnology approaches for HIV/AIDS treatment and prevention”. Nanomedicine, 5 (2010) 269. Full Text

48.  Chan JM, Zhang L,Tong R, Ghosh D, Gao W, Liao G, Yuet KP, Gray D, Rhee J, Cheng J, Golomb G, Libby P, Langer R and Farokhzad OC. “Spatiotemporal controlled delivery of nanoparticles to injured vasculature”. Proc Natl Acad Sci U S A, 107 (2010) 2213. Full Text


47.  Farokhzad OC and Langer R.”Impact of nanotechnology on drug delivery.” ACS Nano, 3 (2009) 16. Full Text

46.  Gu F, Langer R and Farokhzad OC. “Formulation/Preparation of functionalized nanoparticles for in vivo targeted drug delivery.” Methods Mol Biol, 544 (2009) 589. Full Text

45.  Bassett EK, Slocum AH, Masiakos PT, Pryor HI 2nd, Farokhzad OC and Karp JM. “Design of a mechanical clutch-based needle-insertion device.” Proc Natl Acad Sci U S A,106 (2009) 5540. Full Text

44.  Salvador-Morales C, Gao W, Ghatalia P, Murshed F, Aizu W, Langer R and Farokhzad OC. “Multifunctional nanoparticles for prostate cancer therapy.” Expert Rev Anticancer Ther, 9( 2009) 211. Full Text

43.  Chan JM, Zhang L, Yuet KP, Liao G, Rhee JW, Langer R and Farokhzad OC. “PLGA-lecithin-PEG core-shell nanoparticles for controlled drug delivery.” Biomaterials, 30 (2009) 1627. Full Text

42.  Salvador-Morales C, Zhang L, Langer R and Farokhzad OC. “Immunocompatibility properties of lipid-polymer hybrid nanoparticles with heterogeneous surface functional groups.” Biomaterials, 30 (2009) 2231. Full Text


41.  Zhang L, Chan JM, Gu FX, Rhee JW, Wang AZ, Radovic-Moreno AF, Alexis F, Langer R and Farokhzad OC.”Self-assembled lipid–polymer hybrid nanoparticles: a robust drug delivery platform.” ACS Nano, 2 (2008) 1696. Full Text

40.  Alexis F, Basto P, Levy-Nissenbaum E, Radovic-Moreno AF, Zhang L, Pridgen E, Wang AZ, Marein SL, Westerhof K, Molnar LK and Farokhzad OC. “HER-2-targeted nanoparticle-affibody bioconjugates for cancer therapy.” ChemMedChem, 3 (2008) 1839. Full Text

39.  Dhar S, Gu FX, Langer R, Farokhzad OC and Lippard SJ. “Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles.” Proc Natl Acad Sci U S A, 105 (2008) 17356. Full Text

38.  Wang AZ, Gu F, Zhang L, Chan JM, Radovic-Moreno A, Shaikh MR and Farokhzad OC. “Biofunctionalized targeted nanoparticles for therapeutic applications.” Expert Opin Biol Ther, 8 (2008) 1063. Full Text

37.  Levy-Nissenbaum E, Radovic-Moreno AF, Wang AZ, Langer R and Farokhzad OC. “Nanotechnology and aptamers: applications in drug delivery.” Trends Biotechnol, 26 (2008) 442. Full Text

36.  Alexis F, Rhee JW, Richie JP, Radovic-Moreno AF, Langer R and Farokhzad OC. “New frontiers in nanotechnology for cancer treatment.” Urol Oncol, 26 (2008) 74. Full Text

35.  Teply BA, Tong R, Jeong SY, Luther G, Sherifi I, Yim CH, Khademhosseini A, Farokhzad OC, Langer RS and Cheng J. “The use of charge-coupled polymeric microparticles and micromagnets for modulating the bioavailability of orally delivered macromolecules.” Biomaterials, 29 (2008) 1216. Full Text

34.  Zhang L, Gu FX, Chan JM, Wang AZ, Langer RS and Farokhzad OC. “Nanoparticles in medicine: therapeutic applications and developments.” Clin Pharmacol Ther, 83 (2008) 761. Full Text

33.  Farokhzad OC.”Nanotechnology for drug delivery: the perfect partnership.” Expert Opin Drug Deliv, 5 (2008) 927. Full Text

32.  Alexis F, Pridgen E, Molnar LK and Farokhzad OC.”Factors affecting the clearance and biodistribution of polymeric nanoparticles.” Mol Pharm, 5 (2008) 505. Full Text

31.  Karnik R, Gu F, Basto P, Cannizzaro C, Dean L, Kyei-Manu W, Langer R and Farokhzad OC.”Microfluidic platform for controlled synthesis of polymeric nanoparticles.” Nano Lett, 8 (2008) 2906. Full Text

30.  Wang AZ, Bagalkot V, Vasilliou CC, Gu F, Alexis F, Zhang L, Shaikh M, Yuet K, Cima MJ, Langer R, Kantoff PW, Bander NH, Jon S and Farokhzad OC. “Superparamagnetic iron oxide nanoparticle-aptamer bioconjugates for combined prostate cancer imaging and therapy.” ChemMedChem, 3 (2008) 1311. Full Text

29.  Gu F, Zhang L, Teply BA, Mann N, Wang A, Radovic-Moreno AF, Langer R and Farokhzad OC. “Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers.” Proc Natl Acad Sci U S A, 105 (2008) 2586. Full Text


28.  Peer D, Karp JM, Hong S, Farokhzad OC, Margalit R and Langer R. “Nanocarriers as an emerging platform for cancer therapy.” Nature Nanotechnology 2 (2007) 751. Full Text

27.  Bagalkot V, Zhang L, Levy-Nissenbaum E, Jon S, Kantoff PW, Langer R and Farokhzad OC. “Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer.” Nano Lett, 7 (2007) 3065. Full Text

26.  Zhang L, Radovic-Moreno AF, Alexis F, Gu FX, Basto PA, Bagalkot V, Jon S, Langer RS and Farokhzad OC. “Co-delivery of hydrophobic and hydrophilic drugs from nanoparticle-aptamer bioconjugates.” ChemMedChem, 2 (2007) 1268. Full Text

25.  Pridgen EM, Langer R and Farokhzad OC. “Biodegradable, polymeric nanoparticle delivery systems for cancer therapy.” Nanomedicine, 2 (2007) 669. Full Text

24.  Cheng J, Teply BA, Sherifi I, Sung J, Luther G, Gu FX, Levy-Nissenbaum E, Radovic-Moreno AF, Langer R and Farokhzad OC. “Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery.” Biomaterials, 28 (2007) 869. Full Text

23.  Park H, Cannizzaro C, Vunjak-Novakovic G, Langer R, Vacanti CA and Farokhzad OC. “Nanofabrication and Microfabrication of Functional Materials for Tissue Engineering.” Tissue Eng, 13 (2007) 1867. Full Text


22.  Farokhzad OC, Dimitrakov JD, Karp JM, Khademhosseini A, Freeman MR and Langer R. “Drug delivery systems in urology–getting smarter.” Urology, 68 (2006) 463. Full Text

21.  Farokhzad OC, Karp JM and Langer R. “Nanoparticle-aptamer bioconjugates for cancer targeting.” Expert Opin Drug Deliv, 3 (2006) 311. Full Text

20.  Bagalkot V, Farokhzad OC, Langer R and Jon S. “An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform.” Angew Chem Int Ed Engl, 45 (2006) 8149. Full Text

19.  Fukuda J, Khademhosseini A, Yeh J, Eng G, Cheng J, Farokhzad OC and Langer R. “Micropatterned cell co-cultures using layer-by-layer deposition of extracellular matrix components.” Biomaterials, 27 (2006) 1479. Full Text

18.  Cheng J, Teply BA, Jeong SY, Yim CH, Ho D, Sherifi I, Jon S, Farokhzad OC, Khademhosseini A and Langer RS. “Magnetically responsive polymeric microparticles for oral delivery of protein drugs.” Pharm Res, 23 (2006) 557. Full Text

17.  Farokhzad OC and Langer R. “Nanomedicine: developing smarter therapeutic and diagnostic modalities.” Adv Drug Deliv Rev, 58 (2006) 1456. Full Text

16.  Bagalkot V, Farokhzad OC, Langer R and Jon S. “An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform.” Angew Chem Int Ed Engl, 45 (2006) 8149. Full Text

15.  Farokhzad OC, Cheng J, Teply BA, Sherifi I, Jon S, Kantoff PW, Richie JP and Langer R. “Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo.” Proc Natl Acad Sci U S A, 103 (2006) 6315. Full Text

Before 2005

14.  Farokhzad OC, Khademhosseini A, Jon S, Hermmann A, Cheng J, Chin C, Kiselyuk A, Teply B, Eng G and Langer R. “Microfluidic system for studying the interaction of nanoparticles and microparticles with cells.” Anal Chem, 77 (2005) 5453. Full Text

13.  Khademhosseini A, Yeh J, Eng G, Karp J, Kaji H, Borenstein J, Farokhzad OC and Langer R. “Cell docking inside microwells within reversibly sealed microfluidic channels for fabricating multiphenotype cell arrays.” Lab Chip, 5 (2005) 1380. Full Text

12.  Farokhzad OC, Jon S, Khademhosseini A, Tran TN, Lavan DA and Langer R. “Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells.” Cancer Res, 64 (2004) 7668. Full Text

11.  Nicolaou F, Teodoridis JM, Park H, Georgakis A, Farokhzad OC, Böttinger EP, Da Silva N, Rousselot P, Chomienne C, Ferenczi K, Arnaout MA and Shelley CS. “CD11c gene expression in hairy cell leukemia is dependent upon activation of the proto-oncogenes ras and j.” Blood, 101 (2003) 4033. Full Text

10.  Shelley CS, Teodoridis JM, Park H, Farokhzad OC, Böttinger EP and Arnaout MA. “During differentiation of the monocytic cell line U937, Pur alpha mediates induction of the CD11c beta 2 integrin gene promoter.” J Immunol, 168 (2002) 3887. Full Text

9.    Song JC, Hanson CM, Tsai V, Farokhzad OC, Lotz M and Matthews JB. “Regulation of epithelial transport and barrier function by distinct protein kinase C isoforms.” Am J Physiol Cell Physiol, 281 (2001) C649. Full Text

8.    Farokhzad OC, Teodoridis JM, Park H, Arnaout MA and Shelley CS. “CD43 gene expression is mediated by a nuclear factor which binds pyrimidine-rich single-stranded DNA.” Nucleic Acids Res, 28 (2000) 2256-67. Full Text

7.    Song JC, Hrnjez BJ, Farokhzad OC and Matthews JB. “PKC-epsilon regulates basolateral endocytosis in human T84 intestinal epithelia: role of F-actin and MARCKS.” Am J Physiol, 277 (1999) C1239. Full Text

6.    Farokhzad OC, Sagar GD, Mun EC, Sicklick JK, Lotz M, Smith JA, Song JC, O’Brien TC, Sharma CP, Kinane TB, Hodin RA and Matthews JB. “Protein kinase C activation downregulates the expression and function of the basolateral Na+/K+/2Cl(-) cotransporter.” J Cell Physiol, 181 (1999) 489. Full Text

5.    Farokhzad OC, Mun EC, Sicklick JK, Smith JA and Matthews JB. “Effects of bryostatin 1, a novel anticancer agent, on intestinal transport and barrier function: role of protein kinase C.” Surgery, 124 (1998) 380. Full Text

4.    Mun EC, Mayol JM, Riegler M, O’Brien TC, Farokhzad OC, Song JC, Pothoulakis C, Hrnjez BJ and Matthews JB. ” Levamisole inhibits intestinal Cl- secretion via basolateral K+ channel blockade.” Gastroenterology, 114 (1998) 1257. Full Text

3.    Farokhzad OC, Shelley CS and Arnaout MA. “Induction of the CD11b gene during activation of the monocytic cell line U937 requires a novel nuclear factor MS-2.” J Immunol, 157 (1996) 5597. Full Text

2.    Böttinger EP, Shelley CS, Farokhzad OC and Arnaout MA. ” The human beta 2 integrin CD18 promoter consists of two inverted Ets cis elements.” Mol Cell Biol, 16 (1994) 2604. Full Text

1. Shelley CS, Farokhzad OC and Arnaout MA. ” Identification of cell-specific and developmentally regulated nuclear factors that direct myeloid and lymphoid expression of the CD11a gene.” Proc Natl Acad Sci U S A, 90 (1993) 5364. Full Text