Inflammation Resolving Nanoparticles.

Inflammation Resolving Nanoparticles.

Excessive inflammation and failed resolution of the inflammatory responses are underlying components of numerous conditions such as arthritis, cardiovascular disease, and cancer. Unfortunately, controlled delivery of the inflammation-resolving therapeutics to lesions is challenging. Thus, we design novel nanoformulations capable of carrying the inflammation-resolving therapeutic drugs to the inflammatory lesions efficiently, and demonstrate their therapeutic efficacy and pro-resolving potential in diverse animal models. This technology provides a step closer to the development of novel therapeutic nanoplatforms for inflammatory disease treatment.


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